How Toxic Stress Derails the Developing Brain

Scientists are discovering the physiologic connections between adversity, stress and academic performance. Children living in poverty are particularly at risk. They often endure toxic stress from adverse experiences, such as exposure to violence, abuse, neglect, loss of a loved one or homelessness. However, toxic stress is not limited to those living below the poverty line.

A recent study by the National Scientific Council on the Developing Child, a multidisciplinary, multi-university collaboration focused on promoting successful learning and adaptive behavior in young children, concluded:

“Extensive research on the biology of stress now shows that healthy development can be derailed by excessive or prolonged activation of stress response systems in the body and the brain, with damaging effects on learning, behavior, and health across the lifespan.”

Frequent activation of the stress response system causes the brain to strengthen those response circuits that can negatively affect behavior long after the stressor in the environment is removed. Sustained activation of the stress response system can also lead to impairments in learning, memory, and the ability to regulate certain stress responses. High, prolonged levels of stress can result in damage to a part of the brain called the hippocampus. This area of the brain is critical to both learning and memory as well as to sometypes of stress response regulation.

Ultimately, this “stress cascade” can impair a child’s executive functioning skills–,e.g., the ability to plan, prioritize and focus on tasks–and create a severe learning disadvantage and poor academic performance. Unfortunately, most schools aren’t designed to address the impact of stress on learning.

This is a gap that many organizations are now working to correct–e.g., Turnaround for Children (mental health awareness in schools), the Edge Foundation (executive functioning coaching in schools) and (greater awareness and understanding of learning disabilities).

How Brains are Built: The Core Story of Brain Development

Learn About Edge Executive Function Coaching


Share on Social Media

2 Responses

  1. Linda

    The Attachment and Trauma Network, a non-profit organization for families (usually adoptive, foster or stepfamilies, also many grandparents raising grandchildren) of children who were traumatized inutero and/or early childhood, has developed a program called Trauma Sensitive Schools, to provide awareness about childhood trauma and how it affects learning, to schools. Please support ATN with your year-end giving.

  2. Dr Charles Parker

    Well said! Very helpful info and excellent video supporting the reality of brain challenges with stress that can, over time become traumatic. We see this frequently with Executive Function compromise with Vets and PTSD as documented by these researchers and clinicians: Many thanks,